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The Parkinson’s Progression Markers Initiative


The Michael J. Fox Foundation launched PPMI in 2010 to better understand Parkinson’s and advance new treatments. Since then, the study has changed how research is done and what scientists know about the brain. It is a cornerstone of our understanding of disease and has heavily influenced clinical trials.

PPMI follows people — with and without Parkinson’s — over time to learn more about how disease starts and changes. That information may lead to insights and tools that can help better diagnose, treat and even prevent brain disease. The study shares its data set — the most robust in Parkinson’s research — with scientists to speed breakthroughs.